产品货号:
Z11211
中文名称:
ARMER/ARL6IP1抗体
英文名称:
Anti-ARMER/ARL6IP1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ARMER/ARL6IP1 Antibody |
指标别名 | Aip 1;AIP1;ARL 6 interacting protein 1;ARL6IP;ARL6IP1;ARMER;KIAA0069 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | ARL6IP1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | ARMER antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human ARMER.The immunogen is located within the last 50 amino acids of ARMER. |
计算分子量 | 23kDa |
成分 | ARMER Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | ARMER Antibody is Ion exchange chromatography purified. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Apoptosis is important for normal development and tissue homeostasis.It is mediated by various caspases and ultimately results in the activation of endogenous endonucleases that degrade cellular DNA.Although apoptosis induced by endoplasmic reticulum (ER) stress is thought to be mediated by caspase-12,other caspases such as caspase-9 are also thought to be activated following ER stress.Recently,ARMER,a novel integral ER-membrane protein was shown to protect cells from ER stress-induced apoptosis.Analysis of the caspase proteolytic cascade suggests that ARMER acts by inhibiting caspase-9 activity,although the mechanism for this remains unkown.It should be noted that ARMER is not related to the inhibitor of apoptosis proteins (IAP) family and does not contain any baculoviral IAP repeat (BIR) domains. |
Uniprot ID | Q15041 |
基因名全称 | ADP-ribosylation factor-like 6 interacting protein 1 |
蛋白名全称 | ADP-ribosylation factor-like 6 interacting protein 1 |
推荐稀释比 | ARMER antibody can be used for detection of ARMER by Western blot at 0.5 to 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2μg/mL.For immunofluorescence start at 2μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in human samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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